Saturday 6 October 2012

Nexiclon XR


Pronunciation: KLOE-ni-deen
Generic Name: Clonidine
Brand Name: Nexiclon XR


Nexiclon XR is used for:

Treating high blood pressure. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.


Nexiclon XR is an alpha agonist. It works by relaxing blood vessels and decreasing heart rate, which lowers blood pressure.


Do NOT use Nexiclon XR if:


  • you are allergic to any ingredient in Nexiclon XR

Contact your doctor or health care provider right away if any of these apply to you.



Before using Nexiclon XR:


Some medical conditions may interact with Nexiclon XR. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have had a skin reaction to the patch form of Nexiclon XR

  • if you have kidney problems, heart problems (eg, irregular heartbeat), problems with the blood vessels in your heart or brain, or the blood disease porphyria

  • if you will be having surgery

  • if you have a history of a stroke or a recent heart attack

  • if you are taking another medicine that contains clonidine

Some MEDICINES MAY INTERACT with Nexiclon XR. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol) because severe and sometimes life-threatening increased blood pressure may occur if Nexiclon XR is suddenly stopped

  • Calcium channel blockers (eg, verapamil) or digoxin because they may increase the risk of Nexiclon XR's side effects, including slow or irregular heartbeat

  • Tricyclic antidepressants (eg, amitriptyline) because they may decrease Nexiclon XR's effectiveness

  • Barbiturates (eg, phenobarbital) because the risk of their side effects may be increased by Nexiclon XR

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nexiclon XR may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Nexiclon XR:


Use Nexiclon XR as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Nexiclon XR by mouth with or without food.

  • Shake well for 5 to 10 seconds before each use.

  • Use the measuring device that comes with Nexiclon XR to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • Insert the adapter into the neck of the bottle. Insert the syringe tip into the adapter and turn the bottle over. Draw out the prescribed amount of Nexiclon XR.

  • Nexiclon XR works best if it is taken at the same time each day, preferably at bedtime unless your doctor tells you differently.

  • Continue to take Nexiclon XR even if you feel well. Do not miss any doses.

  • If you miss a dose of Nexiclon XR, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nexiclon XR.



Important safety information:


  • Nexiclon XR may cause drowsiness, dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Nexiclon XR with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Nexiclon XR may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Talk to your doctor before using alcohol or medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Nexiclon XR; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • Tell your doctor or dentist that you take Nexiclon XR before you receive any medical or dental care, emergency care, or surgery.

  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.

  • If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.

  • If you experience dry mouth, use sugarless candy or gum, or melt bits of ice in your mouth to help keep your mouth moist.

  • Do not suddenly stop taking Nexiclon XR without talking to your doctor. Nervousness, agitation, confusion, tremor, and headache may occur. These may be followed by a rapid, severe rise in blood pressure. You may be at greater risk if you use high doses or if you also take a beta-blocker (eg, propranolol). If you need to stop taking Nexiclon XR, follow your doctor's instructions for slowly decreasing your dose.

  • Contact your doctor if you develop an illness that includes vomiting or if you vomit soon after you take Nexiclon XR.

  • Lab tests, including blood pressure, may be performed while you take Nexiclon XR. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Nexiclon XR with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness.

  • Nexiclon XR should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed. Children may be more sensitive to withdrawal symptoms after suddenly stopping Nexiclon XR.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nexiclon XR while you are pregnant. Nexiclon XR is found in breast milk. If you are or will be breast-feeding while you use Nexiclon XR, check with your doctor. Discuss any possible risks to your baby.

If you suddenly stop taking Nexiclon XR, you may experience WITHDRAWAL symptoms, including nervousness, agitation, headache, tremor, and rapid increase in blood pressure. Do not suddenly stop taking Nexiclon XR without checking with your doctor.



Possible side effects of Nexiclon XR:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; dizziness; drowsiness; dry mouth; headache; nausea; tiredness; trouble sleeping.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); blurred vision or other vision changes; chest pain; decreased sexual desire or ability; fainting; fast, slow, or irregular heartbeat; hallucinations; mental or mood changes (eg, anxiety, agitation, depression, nervousness, restlessness); severe or persistent headache or dizziness; shortness of breath; swelling of the hands, ankles, or feet; unusual bruising or bleeding.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Nexiclon XR side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; decreased body temperature (feeling very cold); decreased reflexes; difficult or slow breathing; fainting; irritability; pinpoint pupils; seizures; severe or persistent dizziness, headache, or drowsiness; slow or irregular heartbeat; weakness.


Proper storage of Nexiclon XR:

Store Nexiclon XR at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Store away from heat, moisture, and light. Keep Nexiclon XR out of the reach of children and away from pets.


General information:


  • If you have any questions about Nexiclon XR, please talk with your doctor, pharmacist, or other health care provider.

  • Nexiclon XR is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nexiclon XR. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nexiclon XR resources


  • Nexiclon XR Side Effects (in more detail)
  • Nexiclon XR Use in Pregnancy & Breastfeeding
  • Nexiclon XR Drug Interactions
  • 0 Reviews for Nexiclon XR - Add your own review/rating


Compare Nexiclon XR with other medications


  • High Blood Pressure

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